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That said, clinical evidence supporting specific dietary eliminations such as gluten or dairy for perioral dermatitis remains limited and mixed as of 2026
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Stromal DHAR was thought to be superfluous, given the fast chemical reduction of dehydroascorbate (DHA) by reduced glutathione (GSH), particularly at alkaline pH (Foyer and Halliwell 1976, 1977)
And it helps maintain copper balance by preventing any theoretical accumulation, even though copper toxicity at recommended doses has never been documented